| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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Wholesale 99% Pharmaceutical Raw Material Sirolimus Rapamycin Powder
CAS 53123-88-9 Rapamycin
| Product Name | Wholesale 99% Pharmaceutical Raw Material Sirolimus Rapamycin Powder CAS 53123-88-9 Rapamycin |
| Appearance | White powder |
| CAS No | 53123-88-9 |
| Molecular Formula | C51H79NO13 |
| Molecular Weight | 914.17 |
| EINECS | 610-965-5 |
| Keywords |
Powder Rapamycin;Material Sirolimus Powder Rapamycin;Purity Rapamycin Powder
|
| Shelf Life | 2 Years Proper Storage |
| Storage | Keep in Cool Dry Place |
Rapamycin is a member of the macrolide immunosuppressant family and a FRAP inhibitor. Rapamycin exhibits binding and inhibitory actions to the FK506 binding protein (FKBP5) proline rotamase via simultaneous binding by FKBP12 and FRAP. FRAP (RAFT1) proteins exhibit homology to PI 4- and PI 3-kinases,which have PI 4-kinase and autophosphorylating activities.The rapamycin/FKBP complex does not inhibit the FRAP PI 4-kinase activity,but does inhibit FRAP autophosphorylation.
Rapamycin is unique in its ability to inhibit lymphokine induced cell proliferation at the G1 and S phase as well as an irreversible cellular arrest at the G1 phase in S. cerevisiae cells.
Rapamycin also exhibits selective signal blocking leading to the activation of p70/85 S6 kinase, which is potentially due to the inhibition of FRAP autophosphorylation or protein kinase activity. Angiogenesis inhibition is also exhibited,possibly through the inhibition of the Akt pathway. Rapamycin is an inhibitor of mTOR.
Function of Rapamycin
Rapamycin is a triene macrolide antibiotic,which demonstrates anti-fungal,anti-inflammatory,anti-tumor and immunosuppressive properties.
Application of Rapamycin
Rapamycin (RAPA) is a novel macrolide immunosuppressant is now often used as a transplanted organ to maintain immunity drugs (especially kidney transplants), to mitigate the immune organ rejection after transplant surgery, but scientists it recently found another purpose: for the treatment of Alzheimer's disease (senile dementia).
Target of rapamycin (mTOR) as an intracellular kinases pathway abnormalities can induce a variety of diseases.
As rapamycin mTOR inhibitor targeting, to treat with this pathway is closely related to tumors, including renal cell carcinoma, lymphoma, lung cancer, liver cancer, breast cancer, neuroendocrine carcinoma and gastric cancer
Xi'an HDM Biotechnology Co., Ltd. was established in 2012. It is a high-tech professional and technical enterprise integrating R & D, production and sales. Located in the world-famous historical capital-the ancient city of Xi'an.
HDM's production base is located in Xi'an, Shaanxi. It covers an area of 35,000 square meters and a building area of 20,000 square meters. It relies on the natural rich plant resources in the mountainous areas and the production bases of Chinese medicinal materials and intermediates in southern Shaanxi. Currently it has three multi-functional plant extraction and purification production lines and one Pilot production line, a GMP production line, and a fully equipped laboratory. HDM Bio is equipped with various detection equipment such as atomic absorption spectrometry,gas chromatography,spectrophotometer,polarimeter,
automatic titrator, biochemical oxygen demand incubator, chemical oxygen demand incubator, high performance liquid chromatography Etc. to ensure product quality.
HDM's main products are plant extracts ,health products,cosmetic raw Materials,veterinary raw materials,
and pharmaceutical raw materials. Most of our products are derived from natural plants. Marketing services are available in many countries around the world, as well as Hong Kong, Macao and Taiwan regions. We have established a good and stable cooperative relationship with more than a hundred pharmaceutical,food,health products and daily chemical manufacturing companies and pharmaceutical raw material traders.
HDM Biotechnology Corporation adheres to the corporate tenet of "scientific rigor, pioneering and innovative, sincere cooperation".
HDM's corporate philosophy: "Integrity first, customer first. Sincere unity, open up the future."
With the improvement of people's quality of life in the new century, along with the vigorous development of the life and health industry, HDM Bio is facing greater opportunities and challenges. We are confident to provide more comprehensive and better scientific and technical services for scientific researchers. HDM will not humiliate its mission and create the future with you!
Q1:Are you a manufacturer or trading company?
A: We are a manufacturer, welcome to visit us.
Q2: What's your MOQ?
A:It depends on different products, we accept sample order or provide free samples for your
testing.
Q3: How to confirm the product quality before placing the order?
A:Sample could be provided, and we have inspection report issued by authoritative third-party
testing agency.
Q4:Can you send products to my country?
A: Sure, we can, we have rich shipping experience to the whole world.
Q5: How about delivery time/method?
A: We usually ship within 1-3 working days after your payment.
We can ship by door to door courier, by air, by sea, you could also use your own shipping
agent, if u have.
Q6. How to solve after-sale disputes?
A: We accept Changing or refunding service if any quality problem, u can pay via Trade
Assurance Order to protect your fund security.
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