| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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Wholesale 99% Anticancer Everolimus Pharmaceutical BHT Everolimus
Powder CAS 159351-69-6 Everolimus
| Product Name | Wholesale 99% Anticancer Everolimus Pharmaceutical BHT Everolimus Powder CAS 159351-69-6 Everolimus |
| Appearance | White powder |
| CAS No | 159351-69-6 |
| Molecular Formula | C53H83NO14 |
| Molecular Weight | 958.22 |
| EINECS | 621-003-9 |
| Keywords |
Everolimus;Everolimus powder;Everolimus price
|
| Shelf Life | 2 Years Proper Storage |
| Storage | Keep in Cool Dry Place |
Everolimus, an orally adminstered rapamycin analog, has recently been approved for treatment of renal cell carcinoma (RCC) refractory to inhibitors of vascular endothelial growth factor (VEGF) receptor signaling. Everolimus significantly increased progression-free survival (median PFS for the everolimus treated group was 4.0 months versus 1.9 months for the placebo group), although tumor regressions were observed only infrequently.
While the target for everolimus, (the serine/threonine kinase mTOR) is well established, the mechanism by which this agent retards tumor growth is not well defined. Further, biomarkers that predict tumor sensitivity are still elusive. The mechanism of action, preclinical antitumor activity, and clinical activity of everolimus against RCC are reviewed.
Function of Everolimus
Everolimus may have a role in heart transplantation, as it has been shown to reduce chronic allograft vasculopathy in such transplants. It also may have a similar role to sirolimus in kidney and other transplants.
Although, sirolimus had generated fears over use of m-TOR inhibitors in liver transplantation recipients, due to possible early
hepatic artery thrombosis and graft loss, use of everolimus in the setting of liver transplantation is promising. Jeng et al., in their study of 43 patients, concluded the safety of everolimus in the early phase after living donor liver transplantation. In their study, no hepatic artery thrombosis or wound infection was noted. Also, a possible role of everolimus in reducing the recurrence of hepatocellular carcinoma after liver transplantation was correlated. A target trough level of 3 ng/mL at 3 months was shown to be beneficial in recipients with pre-transplant renal dysfunction. In their study, 6 of 9 renal failure patients showed significant recovery of renal function, whereas 3 showed further deterioration, one of whom required hemodialysis.
Application of Everolimus
Xi'an HDM Biotechnology Co., Ltd. was established in 2012. It is a high-tech professional and technical enterprise integrating R & D, production and sales. Located in the world-famous historical capital-the ancient city of Xi'an.
HDM's production base is located in Xi'an, Shaanxi. It covers an area of 35,000 square meters and a building area of 20,000 square meters. It relies on the natural rich plant resources in the mountainous areas and the production bases of Chinese medicinal materials and intermediates in southern Shaanxi. Currently it has three multi-functional plant extraction and purification production lines and one Pilot production line, a GMP production line, and a fully equipped laboratory. HDM Bio is equipped with various detection equipment such as atomic absorption spectrometry,gas chromatography,spectrophotometer,polarimeter,
automatic titrator, biochemical oxygen demand incubator, chemical oxygen demand incubator, high performance liquid chromatography Etc. to ensure product quality.
HDM's main products are plant extracts ,health products,cosmetic raw Materials,veterinary raw materials,
and pharmaceutical raw materials. Most of our products are derived from natural plants. Marketing services are available in many countries around the world, as well as Hong Kong, Macao and Taiwan regions. We have established a good and stable cooperative relationship with more than a hundred pharmaceutical,food,health products and daily chemical manufacturing companies and pharmaceutical raw material traders.
HDM Biotechnology Corporation adheres to the corporate tenet of "scientific rigor, pioneering and innovative, sincere cooperation".
HDM's corporate philosophy: "Integrity first, customer first. Sincere unity, open up the future."
With the improvement of people's quality of life in the new century, along with the vigorous development of the life and health industry, HDM Bio is facing greater opportunities and challenges. We are confident to provide more comprehensive and better scientific and technical services for scientific researchers. HDM will not humiliate its mission and create the future with you!
Q1:Are you a manufacturer or trading company?
A: We are a manufacturer, welcome to visit us.
Q2: What's your MOQ?
A:It depends on different products, we accept sample order or provide free samples for your
testing.
Q3: How to confirm the product quality before placing the order?
A:Sample could be provided, and we have inspection report issued by authoritative third-party
testing agency.
Q4:Can you send products to my country?
A: Sure, we can, we have rich shipping experience to the whole world.
Q5: How about delivery time/method?
A: We usually ship within 1-3 working days after your payment.
We can ship by door to door courier, by air, by sea, you could also use your own shipping
agent, if u have.
Q6. How to solve after-sale disputes?
A: We accept Changing or refunding service if any quality problem, u can pay via Trade
Assurance Order to protect your fund security.
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